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Levitra is an oral drug designed to treat male erectile dysfunction. Also known by its pharmacological name of Vardenafil hydrochloride, this drug increases blood flow to the penis to allow an erection to occur. Generally speaking, this drug is both effective and well tolerated, and allows its users to return to a normal sex life. Although it must be taken in advance of sexual activity, it lasts a relatively long time in the bloodstream, allowing its users to enjoy intimacy on a reasonable schedule.

How Does Levitra Work?

An erection starts with the nerves in and around the penis that receive sexual stimulation releasing nitric oxide. The increased nitric oxide levels cause the body to release a chemical called cyclic guanosine monophosphate (cGMP). This chemical causes the muscle tissue in the penis to relax, allowing blood to flow in, causing the erection. The body uses a class of chemicals called phosophodiesterases (PDEs) to regulate cGMP levels. If PDE levels are too high, they will block cGMP, preventing erection. Levitra blocks the body from releasing the cGMP-specific phosphodiesterase type 5 enzyme (PDE5). Since PDE5 is the most prevalent PDE in that part of the body, blocking it allows erections to occur. Levitra does not significantly block other PDEs, limiting its impact on other body functions.

Levitra Dosages

Levitra, manufactured by Bayer - comes in a film-coated tablet which is round and orange. Tablets are marked with "Bayer" on one side and with the dosage on the other side. Levitra tablets are sold in 2.5mg, 5mg, 10mg and 20mg doses. The pill contains a number of other inert ingredients such as colloidal silicon dioxide, microcrystalling cellulose and both yellow and red ferric oxides, which serve as coloring agents.

How Long Does Levitra Last?

Levitra typically takes one hour to reach full effect, although if it is taken after a large and fatty meal, it can take a little bit longer. It should last for four to five hours, meaning that it will make it possible to obtain an erection with sexual stimulation. The drug should not lead to an erection which lasts for four to five hours, though.

Levitra Side Effects

Most people who take Vardenafil Hcl for their erectile dysfunction experience few, if any, side effects. Some experience mild effects such as stomach discomfort, headache or dizzyness, although these are common with many drugs. At times, Levitra can cause those who take it to have trouble distinguishing between blue and green. This side effect should gradually go away as the drug wears off. To avoid dizziness, Levitra's manufacturer recommends that its users get up slowly when they are sitting or laying down. If Levitra causes a complete loss of vision in either or both eyes, though, the user may be experiencing a more serious side effect which requires immediate medical attention.
Since sex is, in and of itself, a strenuous activity, users of Levitra should be in adequate health to engage in sex. This is especially of concern for individuals who have cardiovascular problems. Another serious potential side effect is priapism--which is a long-lasting and painful erection. Levitra can also cause a sudden onset of tinnitus or of other hearing problems. In any of these cases, the affected patient should immediately seek medical help.

Who Should Not Take Levitra?

People with cardiovascular issues such as high blood pressure, angina, or heart attack should, at a minimum, let their prescribing doctor know before taking Levitra. This is especially important for patients who use nitroglycerin or other nitrate drugs, since they can have a dangerous interaction with Vardenafil. In addition to heart problems, patients who are allergic to Levitra or any of the inert ingredients in the table should avoid it. Finally, the elderly should be careful taking Levitra as its side effects tend to be more pronounced with older patients.

What Other Medications Will Affect Levitra?

Although the interaction between Levitra and nitrate drugs like nitroglycerin is well known, Levitra can also have a dangerous interaction with nitroprusside and with "poppers," which are recreational drugs such as butyl nitrite and amyl nitrite. Vardenafil hcl also has the potential for interactions with alpha blockers, liver enzyme regulator, some anti-seizure medications and drugs for hypertension. Drugs with affect the rhythm of the heart can also interact with Levitra, leading to the potential for QT prolongation, which can be dangerous. Certain anti-viral, anti-fungal and antibiotic medications also can interact with Levitra, necessitating lower dosage. Finally, Levitra should never be mixed with other medications that treat erectile dysfunction.
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